CH-Alpha Osteo Fortibone® (Rebuild Bone Density & Prevent Fractures) with Calcium Lactate - 1 Box

Clinicals

FORTIBONE^® – THE MISSING PIECE IN BONE HEALTH MANAGEMENT

Bones need more than calcium
Calcium supplements are everywhere, yet more and more people are suffering from osteoporosis and osteopenia. Bone is a mixture of mineral crystals held in an organic collagen matrix. On their own, the crystals would be extremely brittle and prone to break. Like a bridge is built out of concrete and steel, collagen in the bones is essential for bone flexibility and elasticity. It is important to keep the skeletal system healthy. Osteoporosis (OP) is a condition characterized by low bone mass and micro-architectural deterioration of bone tissue, which leads to enhanced bone fragility and a consequent increase in fracture risk¹. Osteopenia, the early stage of osteoporosis, can begin at the age of 35 years when bone mass progressively declines.² The likelihood to get a fracture increases with age. The risk of contracting a bone fracture is doubling every ten years in both genders.³

FORTIBONE^® stimulates the synthesis of bone collagen matrix
The specific peptides of FORTIBONE^® stimulate bone cells to increase the synthesis of bone components such as collagen. They have a kind of ‘signaling effect’ on osteoblasts to counterbalance the collagen degradation in the extracellular bone matrix, which is the essential framework for bone mineralization. In addition, FORTIBONE^® influences degenerative processes in bones by reducing osteoclast activity. The result is a considerably higher synthesis of collagenous bone matrix.

Bone metabolism

Bone mineral density measurement

 

Bone mass increase in the spine

Clinically proven to promote bone health
A single-center, prospective, randomized, placebo-controlled, double-blinded study showed the potential of FORTIBONE^®. Over a period of 12 months, 180 women with reduced bone mass participated in a therapy with daily intake of 5 g FORTIBONE^® or placebo. Changes in bone mass density were measured in the spine and femoral neck of the participants detected by DXA scans.

FORTIBONE^® consumption showed a significant improvement of bone density. The results showed a pronounced increase in BMD (Bone Mineral Density) after FORTIBONE^® supplementation in women suffering from osteopenia or osteoporosis. The results indicate an anabolic effect. FORTIBONE^® is an interesting option to counteract bone degeneration.

Changes in bone mineral density


Promising results
The results of this study indicated an anabolic effect, showing a pronounced increase in bone mineral density after FORTIBONE® supplementation. In the femoral neck, BMD increased by 6.7%, whereas in the spine results showed an increase of 3% at the end of the treatment phase. In the same period, bone density in the placebo group decreased by 1.3% in the spine and 1% in the femoral neck. Hence, at the end of the study, subjects in the collagen peptides group showed significantly increased BMD compared to placebo with a 4.2% higher BMD in the spine and a 7.7% higher BMD in the femoral neck.

¹ ALVES RD, DEMMERS JA, BEZSTAROSTI K, VAN DER EERDEN BC, VERHAAR JA, EIJKEN M, VAN LEEUWEN JP (2011) UNRAVELING THE HUMAN BONE MICROENVIRONMENT BEYOND THE CLASSICAL EXTRACELLULAR MATRIX PROTEINS: A HUMAN BONE PROTEIN LIBRARY. J PROTEOME RES 10:4725-4733

² RAISZ LG (2005) PATHOGENESIS OF OSTEOPOROSIS: CONCEPTS, CONFLICTS, AND PROSPECTS.
J CLIN INVEST 115:3318-3325

³ COLE ZA, DENNISON EM, COOPER C (2009) THE IMPACT OF METHODS FOR ESTIMATING BONE HEALTH AND THE GLOBAL BURDEN OF BONE DISEASE. SALUD PUBLICA MEX 51 SUPPL 1:S38-S45

Risk Category Osteoporosis

*COLE ZA, DENNISON EM, COOPER C (2009) THE IMPACT OF METHODS FOR ESTIMATING BONE HEALTH AND THE GLOBAL BURDEN OF BONE DISEASE. SALUD PUBLICA MEX 51 SUPPL 1:S38-S45